Abstract
Central motor conduction time (CMCT) and regional cerebral blood flow were investigated
in 21 patients with leuko-araiosis. The severity of dementia was examined using mini-mental
state examination. The head magnetic stimulation was performed using an SMN-1100 magnetic
stimulator and a round coil with a diameter of 17 cm. The regional cerebral blood
flow was measured using the stable xenon computed tomography method. The CMCT was
significantly longer in the patients with dementia than in the patients without dementia.
The blood flows in the parietal cortex, frontal white matter and thalamus were significantly
lower in the patients with dementia than in the patients without dementia. There were
significant negative correlations between the CMCT and the blood flows in the frontal
cortex, temporal cortex, frontal white matter and thalamus. The significant negative
correlations suggest that the prolongation of CMCT in patients with leuko-araiosis
is related to the decrease in regional cerebral blood flows.
Keywords
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Article info
Publication history
Accepted:
May 18,
1998
Received in revised form:
May 15,
1998
Received:
February 12,
1998
Identification
Copyright
© 1998 Elsevier Science B.V. Published by Elsevier Inc. All rights reserved.
