Highlights
- •Larger SVS width predicted good recanalization following endovascular thrombectomy.
- •The cut-off value of the SVS width to predict successful recanalization was 4.2 mm.
- •Patients with larger SVS width were more likely to achieved first-pass reperfusion.
Abstract
Background and purpose
We aimed to investigate the relationship between arterial recanalization following
endovascular therapy and the susceptibility vessel sign (SVS) length and width on
susceptibility-weighted imaging.
Methods
We retrospectively evaluated consecutive patients with anterior circulation ischemic
stroke who underwent magnetic resonance imaging preceded endovascular therapy, and
measured the SVS length and width. Successful recanalization was defined as expanded
thrombolysis in cerebral infarction grade of 2b to 3. Logistic regression analysis
was executed to determine the independent predictors of successful recanalization
and first-pass reperfusion (FPR) after endovascular therapy.
Results
Among 100 patients, successful recanalization and FPR were observed in 77 and 34 patients,
respectively. The median SVS length and width were 10.3 mm (interquartile range, 6.8–14.1 mm)
and 4.2 mm (interquartile range, 3.1–5.2 mm), respectively. In multivariate logistic
regression analysis, SVS width was associated with successful recanalization (odds
ratio, 1.88; 95% confidence interval, 1.14–3.07; p = 0.005) and FPR (odds ratio, 1.38; 95% confidence interval, 1.01–1.89; p = 0.039). The optimal cutoff value for the SVS width to predict successful recanalization
and FPR were 4.2 mm and 4.0 mm, respectively.
Conclusions
Larger SVS width may predict successful recanalization and FPR following endovascular
therapy.
Keywords
Abbreviations:
DWI (diffusion-weighted imaging), ICA-T (internal carotid artery terminus), IQR (interquartile range), IV-tPA (intravenous tissue-type plasminogen activator), MCA (middle cerebral artery), MRA (magnetic resonance angiography), MRI (magnetic resonance imaging), eTICI (expanded thrombolysis in cerebral infarction), FPR (First-pass reperfusion), NIHSS (National Institute of Health Stroke Scale), SVS (susceptibility vessel sign), SWI (susceptibility-weighted imaging)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: February 12, 2023
Accepted:
February 9,
2023
Received in revised form:
February 5,
2023
Received:
September 19,
2022
Identification
Copyright
© 2023 Elsevier B.V. All rights reserved.
