- •Chimeric antigen receptor (CAR) T-cell therapy is a revolutionary therapeutic breakthrough for certain cancers.
- •The potential effect of CAR T therapy on cognitive functions is a concern.
- •Findings from current studies have shown varied results.
- •Some studies have suggested that the adverse effects on cognition are potentially reversible.
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- Change in neurocognitive performance among patients with non-Hodgkin lymphoma in the first year after chimeric antigen receptor T cell therapy.Transplant Cell Ther. 2022; 28: 305.e1-305.e9
- Neurological management and work-up of neurotoxicity associated with CAR T cell therapy.Neurol. Res. Pract. 2022; 4: 1
- Description of neurotoxicity in a series of patients treated with CAR T-cell therapy.Sci. Rep. 2020; 10: 18997
- Patient-reported neuropsychiatric outcomes of long-term survivors after chimeric antigen receptor T cell therapy.Biol. Blood Marrow Transplant. 2020; 26: 34-43
- Systematic evaluation of neurotoxicity in children and young adults undergoing CD22 chimeric antigen receptor-T cell therapy.J. Immunother. 2018; 41: 350-358
- Evaluation of mid-term (6-12 months) neurotoxicity in B-cell lymphoma patients treated with CAR T cells: a prospective cohort study.Neuro-Oncology. 2021; 23: 1569-1575
- Patient perspectives on health-related quality of life in diffuse large B-cell lymphoma treated with Car T-cell therapy: a qualitative study.Oncol. Ther. 2022; 10: 123-141
- Patient-reported symptom and functioning status during the first 12 months after chimeric antigen receptor T cell therapy for hematologic malignancies.Transplant Cell Ther. 2021; 27: 930.e1-930.e10
- Perceived cognitive changes following chimeric antigen receptor T cell therapy in lymphoma: perceptual anticipation?.Transplant Cell Ther. 2022; S2666-6367 (01628–1)
- QEEG indices are associated with inflammatory and metabolic risk factors in Parkinson’s disease dementia: an observational study.EClinicalMedicine. 2022; 52: 101615https://doi.org/10.1016/j.eclinm.2022.101615
- Cerebral small vessel disease alters neurovascular unit regulation of microcirculation integrity involved in vascular cognitive impairment.Neurobiol. Dis. 2022; 170: 105750
- Lipoprotein-associated phospholipase A2 and superoxide dismutase are independent predicators of cognitive impairment in cerebral small vessel disease patients: diagnosis and assessment.Aging Dis. 2019; 10: 834-846