Posterior cortical atrophy (PCA) is a rare neurodegenerative syndrome that primarily
affects the parietal and occipital lobes and is typified by striking early deficits
in higher visuospatial processing, numeracy and literacy. In this talk we will review
recent developments in the clinical, cognitive, imaging, pathological and genetic
characterisation of the syndrome. Linked to recent increased interest in biological
subtypes of AD, we will also consider heterogeneity within the PCA syndrome and overlap
with related clincial presentations, and the broad notion of PCA as an extreme point
in a continuum of phenotypical variation. Finally we will examine the changing and
distinctive care, management and support needs of those living with PCA and look at
promising non-pharmarcological interventions and strategies.
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