Neurobiology of psychogenic non-epileptic events

      NEUROBIOLOGY OF PSYCHOGENIC NONE-EPILEPTIC EVENTS Psychogenic non-epileptic events/eizure (PNES) are disabling and frequent. The diagnosis is based on clinical features and is reliable. However, misconception about the neurobiology of PNES prevents a good communication of the diagnosis and many patients and/or caregivers avoid clarifying or naming the diagnosis as there is a fear to address the issue of what “psychogenic” may mean and represent in terms of stigmatization. This talk will highlight what neurosciences has found over the last decades to better understand the neurobiology of PNES and how brain mechanisms may be involved in this disorder. It will address the question of misconception and myths surrounding the diagnosis of PNES. It will show that neural networks (motor control, multimodal integration, emotion regulation, attention) play a role in the disorder along with genetic and environmental (bio-psycho-social) factors.
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