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Neuropeptides and channels: Data from clinical trials and experimental models

      Progress in understanding the pathogenesis underlying migraine has been made with the identification of signaling molecules that are involved in the genesis of a migraine attack. This advance has facilitated the development of mechanism-based therapies for migraine. In my presentation I will review the current understanding of the pathogenesis of migraine, which is based predominantly on clinical data published within the past 10 years, and outline recommended practices for the treatment of acute migraine and for preventive treatment of migraine, emphasizing medications that have recently been approved.
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