Migraine is well known by the headache itself, however there are many other signals
and symptoms that can occur during an attack. Some symptoms, called premonitory symptoms,
such as yawning and feeling tired, occur in 72–84% of patients. About 20% of migraineurs
present aura. The most common aura is visual disturbances, following by sensitive
symptoms. The headache of migraine is characterized by pulsatile unilateral pain,
of moderate to severe intensity, that worsen by routine physical activities, associated
with photo/phonofobia, nausea and vomiting. About 68–80% of migraine patients present
the last phase called postdrome or resolution, in which the most common symptoms are
tiredness and cognitive difficulties. This lecture will discuss the pathophysiological
aspects of the main signals and symptoms of a migraine attack.
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