Highlights
- •The “hypointense substantia nigra sign” (HSNS) is a novel MRI sign present in PSP.
- •The HSNS is a well-defined hypointense area at the medial substantia nigra in T1 images.
- •The HSNS is highly specific for progressive supranuclear palsy (PSP).
- •The HSNS is more specific but less sensitive for PSP compared to the “Hummingbird sign”.
Keywords
Abbreviations:
PSP (progressive supranuclear pasly), NPH (normal pressure hydrocephalus), HSN (hypointense substatnia nigra), PD (Parkinson's disease), MSA (multiple system atrophy), CBD (corticobasal degeneration), PSP-HSN (PSP with HSN sign), PSP-nHSN (PSP without HSN sign), SN (substantia nigra), SNr (substantia nigra pars reticulata), SNc (substantia nigra pars compacta.)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: December 20, 2020
Accepted:
December 17,
2020
Received in revised form:
December 6,
2020
Received:
October 29,
2020
Identification
Copyright
© 2020 Elsevier B.V. All rights reserved.
