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Letter to the Editor| Volume 404, P112-114, September 15, 2019

Eyes and hands oscillation in HIV-associated neurocognitive disorder: A case report

Published:July 24, 2019DOI:https://doi.org/10.1016/j.jns.2019.07.030
Eyes and hands oscillation in HIV-associated neurocognitive disorder: A case report
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      In patients with HIV-associated neurocognitive disorder (HAND), movement disorders, including tremor or broken-eye-movement are reported [
      • Smail R.C.
      • Brew B.J.
      HIV-associated neurocognitive disorder.
      in: Handbook of Clinical Neurology. vol. 152. 2018: 75-97
      ]. However to our knowledge, there are no reports that evaluated details of movement disorders in HAND. We present a patient with HAND who was evaluated the development of opsoclonus and hand tremor. After treatment with combined-antiretroviral-therapy, these symptoms ameliorated and thalamic lesion on MRI disappeared. In addition, increased cerebellar blood flow was visualized by applying subtraction ictal SPECT co-registered to MRI (SISCOM) [
      • O'Brien T.J.
      • So E.L.
      • Hauser M.F.
      • Brinkmann B.H.
      • et al.
      Subtraction ictal SPECT co-registered to MRI improves clinical usefulness of SPECT in localizing the surgical seizure focus.
      Neurology. 1998; 50: 445-455
      ].

      Keywords

      Abbreviations:

      HAND (HIV-associated neurocognitive disorder), SISCOM (subtraction ictal SPECT co-registered to MRI), GABAA (gamma-aminobutyric acid A)
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      Article info

      Publication history

      Published online: July 24, 2019
      Accepted: July 23, 2019
      Received in revised form: July 22, 2019
      Received: May 23, 2019

      Identification

      DOI: https://doi.org/10.1016/j.jns.2019.07.030

      Copyright

      © 2019 Elsevier B.V. All rights reserved.

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