Highlights
- •We carried out the first nationwide survey of superficial hemosiderosis (SHS) in Japan.
- •Since over 100 individuals of SHS were confirmed, SHS may not be rare clinical condition.
- •It is important to carry our high magnetic filed MRI using T2* or SWI to identify SHS.
Abstract
Background
The Japanese guideline for diagnosis and classification of superficial hemosiderosis
(SHS) has recently been published, for which patient medical expenses are supported
by the Ministry of Health. We sought to clarify the clinical features, method of diagnosis,
and treatment for SHS in Japan.
Methods
We sent a questionnaire survey to 792 medical institutes of the Japanese Society of
Neurology, to collect information about SHS, including patients during 2017.
Results
We received replies from 287 institutes (36.2%). Estimated total number of patients
with SHS in 2017 was 129 at 55 institutes. All patients were diagnosed by neurologists.
Among 123 patients with available data, 81 patients (63%) had “classical” type (c-SHS),
29 (24%) had “localized” type (l-SHS), and 13 patients (10%) had “atypical” type (a-SHS).
Five patients with l-SHS were excluded because of lacking detailed information. There
were available data for the cause of SHS in 77 patients (63%): 55 (69%) with c-SHS,
16 (55%) with l-SHS, and 6 (48%) with a-SHS. Pharmacological or surgical treatment
was given at 31 institutes. Medical expense subsidies were filed for 41% of patients.
Conclusions
Using the Japanese guideline for diagnosis of SHS, over 100 patients were confirmed
as having SHS with characteristic clinical features. SHS is not a rare clinical condition
in Japan.
Keywords
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Article info
Publication history
Published online: July 17, 2019
Accepted:
July 16,
2019
Received in revised form:
June 24,
2019
Received:
May 26,
2019
Identification
Copyright
© 2019 Elsevier B.V. All rights reserved.
