Highlights
- •Tank-binding kinase 1 is a causal gene for familial Amyotrophic Lateral Sclerosis.
- •Phenotypes associated with Tank-binding kinase 1 mutations are heterogeneous.
- •Primary lateral sclerosis is a rare form of motor neuron disorder.
- •Tank-binding kinase 1 should be tested also in Primary lateral sclerosis phenotype with family history.
Keywords
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Article info
Publication history
Published online: June 27, 2019
Accepted:
June 26,
2019
Received in revised form:
June 14,
2019
Received:
April 22,
2019
Identification
Copyright
© 2019 Elsevier B.V. All rights reserved.
