Highlights
- •Epilepsy surgeries in western China has not risen with years.
- •Patient age at surgery or epilepsy duration has not changed with years.
- •Hippocampal sclerosis was the most frequent type of drug-resistant TLE.
Abstract
Objective
Despite the strong evidence for the efficacy of surgery to treat temporal lobe epilepsy,
the number of such surgeries has plateaued in western countries. This study examined
trends in the number of epilepsy cases diagnosed, number of surgeries performed, and
certain characteristics of surgery patients in western China between January 2009
and December 2017.
Methods
Data were obtained for a population-based sample from a healthcare information system,
as well as for a patient population from West China Hospital. Age at epilepsy onset,
age at surgery, duration of epilepsy, and type of epilepsy pathology based on surgical
samples were analyzed.
Results
Data were obtained for 14,710 hospitalizations from the healthcare system and 17,302
hospitalizations from West China Hospital. The number of hospitalizations, but not
the number of epilepsy surgeries, increased during the study period. Patients' age
at epilepsy onset, age at surgery or epilepsy duration did not change significantly
during the study period.
Significance
Our analysis suggests that in western China, as in western countries, the number of
temporal epilepsy surgeries has plateaued. In contrast, disease-modifying factors
have not changed over time in western China. Further studies are needed to explore
what may contribute to these findings.
Keywords
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Article info
Publication history
Published online: June 25, 2019
Received in revised form:
June 22,
2019
Received:
April 15,
2019
Identification
Copyright
© 2019 Elsevier B.V. All rights reserved.
