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Letter to the Editor| Volume 403, P119-121, August 15, 2019

Varicella-zoster virus vasculopathy in a multiple sclerosis patient on fingolimod

  • Author Footnotes
    1 These authors contributed equally to the manuscript.
    Alexandra Muccilli
    Footnotes
    1 These authors contributed equally to the manuscript.
    Affiliations
    Division of Neurology, Department of Medicine, Centre Hospitalier de l'Université de Montréal (CHUM), University of Montreal, Montreal, Québec, Canada

    Department of Neurology, University of California, San Francisco, United States of America
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  • Author Footnotes
    1 These authors contributed equally to the manuscript.
    Ahmad Nehme
    Correspondence
    Corresponding author at: Centre Hospitalier de l'Université de Montréal, 1051 Rue Sanguinet, Montreal, Quebec H2X 3E4, Canada.
    Footnotes
    1 These authors contributed equally to the manuscript.
    Affiliations
    Division of Neurology, Department of Medicine, Centre Hospitalier de l'Université de Montréal (CHUM), University of Montreal, Montreal, Québec, Canada
    Search for articles by this author
  • Marilyn Labrie
    Affiliations
    Division of Neurology, Department of Medicine, Centre Hospitalier de l'Université de Montréal (CHUM), University of Montreal, Montreal, Québec, Canada
    Search for articles by this author
  • Marc Girard
    Affiliations
    Division of Neurology, Department of Medicine, Centre Hospitalier de l'Université de Montréal (CHUM), University of Montreal, Montreal, Québec, Canada
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  • Celine Odier
    Affiliations
    Division of Neurology, Department of Medicine, Centre Hospitalier de l'Université de Montréal (CHUM), University of Montreal, Montreal, Québec, Canada
    Search for articles by this author
  • Alexandre Y. Poppe
    Affiliations
    Division of Neurology, Department of Medicine, Centre Hospitalier de l'Université de Montréal (CHUM), University of Montreal, Montreal, Québec, Canada
    Search for articles by this author
  • Author Footnotes
    1 These authors contributed equally to the manuscript.
Published:June 26, 2019DOI:https://doi.org/10.1016/j.jns.2019.06.025
Varicella-zoster virus vasculopathy in a multiple sclerosis patient on fingolimod
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      Highlights

      • •
        Fingolimod treatment may be associated with VZV vasculopathy in MS patients.
      • •
        Fingolimod related VZV vasculopathy can develop in the absence of prior shingles.
      • •
        Lymphopenia is a risk factor for fingolimod-associated VZV reactivation.

      Keywords

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      Article Info

      Publication History

      Published online: June 26, 2019
      Accepted: June 24, 2019
      Received in revised form: June 14, 2019
      Received: May 26, 2019

      Identification

      DOI: https://doi.org/10.1016/j.jns.2019.06.025

      Copyright

      © 2019 Elsevier B.V. All rights reserved.

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