Highlights
- •Chromosome 5p deletion (5p-) syndrome may present with neurodegenerative features.
- •5p- pathology is variable possibly with olfactory aplasia and/or polymicrogyria.
- •5p- pathology includes cerebral neuronal inclusions like cortical Lewy bodies.
- •5p- pathology may show α-Synucleinopathy in the limbic and paralimbic cortex.
- •α-Synucleinopathy may be involved in the pathophysiology of 5p- syndrome.
Keywords
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Article info
Publication history
Published online: June 03, 2019
Accepted:
May 31,
2019
Received in revised form:
May 15,
2019
Received:
February 28,
2019
Identification
Copyright
© 2019 Elsevier B.V. All rights reserved.
