The frequency of neurologic manifestations in Behçet's disease (BD) ranges between 5% and 15% [
]. Central nervous system manifestations are represented by parenchymal involvement, which includes brainstem involvement, hemispheric manifestations, spinal cord lesions, and meningo-encephalitic presentations and non parenchymal involvement, including dural sinus thrombosis, arterial occlusion, and/or aneurysms. The association of parenchymal and vascular manifestations is extremely rare [
- Peño I.C.
- De lasHerasRevilla V.
- Carbonell B.P.
- Di CapuaSacoto D.
- Ferrer M.E.
- García-Cobos R.
- González R.A.
Neurobehçet disease: clinical and demographiccharacteristics.
Eur. J. Neurol. 2012 Sep; 19: 1224-1227
]. Among the neuro-vasculo-Behçet's disease patients, venous thrombosis is well-known while arterial involvement has rarely been reported and seldom concerned cerebral arteries. We describe here a stroke case revealing neuro-Behçet's disease (NBD) with parenchymal involvement and extensive vascular lesions interesting several intracranial and systemic arteries. To the best of our knowledge, this is the first reported case of Behçet's disease manifesting as concomitant involvement of systemic and cerebral arteries.
- Saadoun D.
- Asli B.
- Wechsler B.
- Houman H.
- Geri G.
- Desseaux K.
- et al.
Long-term outcome of arterial lesions in Behcet disease: a series of 101 patients.
Medicine (Baltimore). 2012; 91: 18-24
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- Neurobehçet disease: clinical and demographiccharacteristics.Eur. J. Neurol. 2012 Sep; 19: 1224-1227
- Long-term outcome of arterial lesions in Behcet disease: a series of 101 patients.Medicine (Baltimore). 2012; 91: 18-24
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Published online: January 26, 2019
Accepted: January 25, 2019
Received: November 19, 2018
© 2019 Elsevier B.V. All rights reserved.