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Opsoclonus-myoclonus-encephalopathy induced by cefepime

  • Karlo J. Lizarraga
    Correspondence
    Corresponding author at: Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, Division of Neurology, University of Toronto, 399 Bathurst Street, McL 7-402, Toronto, ON M5T 2S8, Canada.
    Affiliations
    Department of Neurology, Jackson Memorial Hospital, University of Miami School of Medicine, Miami, FL, USA

    The Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, Division of Neurology, Department of Medicine, University of Toronto, Toronto, ON, Canada
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  • Deborah O. Heros
    Affiliations
    Department of Neurology, Jackson Memorial Hospital, University of Miami School of Medicine, Miami, FL, USA
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  • David Adams
    Affiliations
    Department of Neurology, Jackson Memorial Hospital, University of Miami School of Medicine, Miami, FL, USA
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  • Anthony E. Lang
    Affiliations
    The Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, Division of Neurology, Department of Medicine, University of Toronto, Toronto, ON, Canada
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  • Andres M. Kanner
    Affiliations
    Department of Neurology, Jackson Memorial Hospital, University of Miami School of Medicine, Miami, FL, USA
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Published:October 31, 2018DOI:https://doi.org/10.1016/j.jns.2018.10.028

      Highlights

      • Opsoclonus might be associated with cefepime neurotoxicity.
      • Cefepime neurotoxicity most commonly presents with myoclonus and encephalopathy.
      • Continuous video-EEG is vital to monitor for non-convulsive status epilepticus.
      • Cefepime neurotoxicity occurs in susceptible patients despite normal renal clearance.

      Keywords

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