- •West Nile virus (WNV) infection has been reported to promote myasthenia gravis (MG) and other autoimmune diseases.
- •Molecular mimicry between WNV proteins and host proteins is postulated as the major mechanism for WNV-triggered autoimmunity.
- •We present a patient with stable ocular MG who progressed to myasthenic crisis after WNV neuroinvasive disease.
- •In stable ocular MG with proven autoantibodies, transformation to generalized MG cannot be attributed to molecular mimicry.
- •Evidence implicates a WNV-induced post-infectious pro-inflammatory state that may amplify and promote autoimmune disease.
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