- •Tardive dyskinesia (TD) remains relatively common, despite the use of second-generation antipsychotics.
- •The Abnormal Involuntary Movement Scale offers a well-accepted solution to assessing dyskinetic movements.
- •There are now two medications approved by regulatory authorities for the treatment of TD: deutetrabenazine and valbenazine.
- •Deutetrabenazine and valbenazine are reversible VMAT2 inhibitors that modulate dopamine signaling by reducing dopamine output, hence reducing the symptoms of TD.
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☆This article is part of the Special Issue Tardive Syndromes and Their Management edited by Robert A. Hauser and Daniel D. Truong.
☆☆A publisher's error resulted in this article appearing in the wrong issue. The article is reprinted here for the reader's convenience and for the continuity of the special issue. For citation purposes, please use; Journal of the Neurological Sciences, 383C, pp. 199-204.