2978| Volume 381, SUPPLEMENT , 1065, October 15, 2017

Lotus protein, an endogenous Nogo receptor antagonist, is involved in inflammation of experimental autoimmune encephalomyelitis

      Background: Axonal degeneration by the Nogo receptor-1 (NgR1) signaling was recently recognized as an important factor in pathogenesis of multiple sclerosis (MS). We previously identified lateral olfactory tract usher substance (LOTUS) as an endogenous NgR1 antagonist and showed that the reduction of LOTUS in the cerebrospinal fluid correlated with the disease activity of MS.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Journal of the Neurological Sciences
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect