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Rituximub for neuromyelitis optica relapses: RIN-1 Study

      Background: Neuromyelitis optica (NMO) is a disorder distinct from multiple sclerosis, and is characterized by the presence of anti-aquaporin4 (AQP4) antibody. Rituximab (RTX), which is a monoclonal antibody against CD-20, is recommended as immunotherapy in guidelines, however, the rationale is based on the results of observational or single-arm studies.
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