2975| Volume 381, SUPPLEMENT , 1064, October 15, 2017

MOG antibody-associated cerebral cortical encephalitis in females

      Background: Myelin oligodendrocyte glycoprotein (MOG) is a myelin protein expressed on the surface of oligodendrocytes and myelin in the central nervous system. MOG is a well-known immunogen for experimental autoimmune encephalomyelitis (EAE). EAE studies have suggested that MOG antibody plays a direct pathogenic role in inflammatory demyelinating disease. Recent studies have demonstrated that MOG antibody is detected in acute disseminated encephalomyelitis (ADEM) and neuromyelitis optica spectrum disorders.
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