“A wise man knows what he does not know.” Yet in the 200 years since James Parkinson identified the “shaking palsy,” it is only in the last
two or three decades that we have come to understand some of what he didn't know we
didn't know, and, thank goodness, it's coming at an increasing rate [
]. We have learned a lot in these years, but we have also learned a lot about our state
of ignorance. And who knows what else is yet to be learned? The harder we look the
harder the problems seem.
Keywords
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References
- Essay on the Shaking Palsy.Sheerwood, Neely and Jones, London1817
- Chronic behavioral disorders of human REM sleep: a new category of parasomnia.Sleep. 1986; 9: 293-308
- Punding on levodopa.Biol. Psychiatry. 1994; 36: 350-351
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- Pramipexole for the treatment of depressive symptoms in patients with Parkinson's disease: a randomised, double-blind, placebo-controlled trial.Lancet Neurol. 2010; 9: 573-580
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Article info
Publication history
Published online: January 04, 2017
Accepted:
January 3,
2017
Received:
December 20,
2016
Identification
Copyright
© 2017 Elsevier B.V. All rights reserved.
