Highlights
- •We assessed the possible predictors and determinants of burden reported by caregivers of PD patients.
- •Social and financial status was disrupted in ~60% to 80% of the caregivers.
- •Motor imbalances with disability and severity of disease are the main factors contributing to burden and stress in caregivers.
- •More advanced stages of PD are associated with increased feeling of burden.
- •75% caregivers were females and experienced mental stress including anxiety and depression.
Abstract
Aim was to analyze predictors of burden among primary caregivers (CGs) of Indian Parkinson's
disease (PD) patients. 150 PD patients were administered using Unified Parkinson's
Disease Rating Scale (UPDRS), Hoehn and Yahr Scale (H&Y), Montgomery Asberg Depression
Rating Score (MADRS) and Mini Mental State Examination (MMSE) in this cross-sectional
evaluation study. CG burden was assessed by Caregiver's Burden Scale (CBS), Hospital
Anxiety and Depression Scale (HADS), SF-36 and 20-item Burden Assessment Schedule
(BAS). Linear regression methods were used to evaluate factors contributing to burden
and stress. Mean age of CG was 50.38 ± 16.04 (range: 25-83 yrs). Marital status of CGs was noted to have significant relationship with CBS score
(F = 9.525, P < 0.0001). Siblings (brother/sister) reported the highest CBS score while the wives
reported the least. Correlations were strong between CBS and HADS anxiety (r = 0.228, P = 0.0048) and HADS depression (r = 0.2172, P = 0.0076). High correlations were found in caregiving duration, patients' stage of illness
and motor disability among all the scales (CBS, HADS, SF36) determined. Step-wise
regression analysis showed UPDRS (beta = 1.364–0.202 ranging among all scales) and H&Y stages (beta = 2.786–7.257) to have the strongest influence on CGs. CGs of patients with depression
(MADRS: P = 0.007 (SF36 mental) and dementia (MMSE: P = 0.01) experienced greater stress. Social and financial status was disrupted in ~60% to 80% of the CGs. Motor imbalances with disability of PD patients and severity
of disease are the main factors contributing to burden and stress in CGs.
Keywords
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Article info
Publication history
Published online: September 03, 2015
Accepted:
September 2,
2015
Received:
August 31,
2015
Identification
Copyright
© 2015 Elsevier B.V. Published by Elsevier Inc. All rights reserved.
