Abstract|Sleep Disorders 1| Volume 357, SUPPLEMENT 1, e96, October 15, 2015

Antidepressant-induced sleep bruxism: Prevalence, incidence, and related factors

      Background: The relationship between sleep bruxism and antidepressant drugs in patients remains unclear.
      Objective: In this study, we aimed to investigate the incidence rate of antidepressant-related bruxism, and to examine whether or not antidepressant use is associated with this side effect in the patients.
      Patients and methods: The study sample was gathered from 2 hospitals. A total of 807 patients who met the criteria of inclusion were included in the study. The sample was divided into 2 groups: antidepressant group (n = 506) and the control group (n = 301). The sleep bruxism was established with reports from the study participants on the basis of the International Classification of Sleep Disorders: Diagnosis and Coding Manual Second Edition.
      Results: The prevalence of bruxism was significantly higher in the antidepressant group (24.3%) than the control group (15.3%). The incidence of antidepressant-induced bruxism was 14.0%. The antidepressants most associated with bruxism were paroxetine, venlafaxine, and duloxetine. The patients experiencing antidepressant-induced bruxism had higher age compared to those who did not suffer from this side effect.
      Conclusions: The results of the present study suggest that bruxism are frequently observed in women taking antidepressants and that it appears to be associated with antidepressant use at least in some patients.