Abstract
Background
About three quarters of stroke deaths occur in developing countries including those
in sub-Saharan African. Short and long-term stroke fatality data are needed for health
service and policy formulation.
Methods
We prospectively followed up from stroke onset, 254 patients recruited from the largest
reference hospitals in Yaounde (Cameroon). Mortality and determinants were investigated
using the accelerated failure time regression analysis.
Results
Stroke mortality rates at one-, six- and 12 months were respectively 23.2% (Ischemic strokes: 20.4%, hemorrhagic strokes: 26.1%,
and undetermined strokes: 34.8, p = 0.219), 31.5% (ischemic strokes: 31.5%, hemorrhagic strokes: 30.4%, and undetermined
strokes: 34.8%, p = 0.927), and 32.7% (ischemic strokes: 32.1%, hemorrhagic strokes: 30.4%, undetermined
strokes: 43.5%, p = 0.496). Fever, swallowing difficulties, and admission NIHSS independently predicted
mortality at one month, six and 12 months. Elevated systolic blood pressure (BP) predicted mortality at one month. Elevated
diastolic blood pressure was a predictor of mortality at one month in participants
with hemorrhagic stroke. Low hemoglobin level on admission only predicted long term
mortality.
Conclusion
In this resource-limited setting, post-stroke mortality was high with 1 out of 5 deaths
occurring at one month and up to 30% deaths at six and twelve months after the index
event. Fever, stroke severity, elevated BP and anemia increased the risk of death.
Our findings add to the body of evidence for the poor outcome after stroke in resource
limited environments.
Keywords
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Article info
Publication history
Published online: August 21, 2015
Accepted:
August 19,
2015
Received in revised form:
July 23,
2015
Received:
May 22,
2015
Identification
Copyright
© 2015 Elsevier B.V. Published by Elsevier Inc. All rights reserved.
