Autosomal recessive spastic ataxia of Charlevoix Saguenay (ARSACS) is a distinct form of hereditary early-onset spastic ataxia and is related to progressive degeneration of the cerebellum and spinal cord [
]. People with ARSACS typically have abnormal tensing of the muscles (spasticity), difficulty coordinating movements (ataxia), muscle wasting (amyotrophy), involuntary eye movements (nystagmus), and speech difficulties (dysarthria).
- Duquette A.
- Brais B.
- Bouchard J.P.
- Mathieu J.
Clinical presentation and early evolution of spastic ataxia of Charlevoix-Saguenay.
Mov. Disord. 2013; 28: 2011-2014https://doi.org/10.1002/mds.25604
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Published online: June 24, 2015
Accepted: June 23, 2015
Received in revised form: June 22, 2015
Received: April 12, 2015
☆All authors declare that they have no conflicts of interest in the present study.
© 2015 Elsevier B.V. Published by Elsevier Inc. All rights reserved.