Letter to the Editor| Volume 352, ISSUE 1-2, P122-124, May 15, 2015

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Fatal intracerebral haemorrhage following intravenous thrombolysis for acute ischaemic stroke: A hidden role for cerebral amyloid angiopathy?

Published:March 26, 2015DOI:
      Thrombolysis with recombinant tissue plasminogen activator (rt-PA) is currently the only approved therapy for acute ischemic stroke. However, intracerebral haemorrhage (ICH) remains the most feared and devastating complication of intravenous thrombolysis [
      • Derex L.
      • Nighoghossian N.
      Intracerebral haemorrhage after thrombolysis for acute ischaemic stroke: an update.
      ]. We report a case of a patient who suffered a catastrophic haemorrhage following intravenous thrombolysis for stroke, related to previously unsuspected severe cerebral amyloid angiopathy (CAA) found on autopsy.


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