Highlights
- •A chronic and prolonged reduction of gastric acidity may impair copper absorption.
- •PPIs have already been significantly associated with vitamin B12 deficiency.
- •PPIs may contribute to copper deficiency.
- •The discontinuation of PPIs should be considered in patients with copper deficiency.
Keywords
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Article info
Publication history
Published online: January 14, 2015
Accepted:
January 6,
2015
Received in revised form:
January 2,
2015
Received:
November 23,
2014
Identification
Copyright
© 2015 Elsevier B.V. Published by Elsevier Inc. All rights reserved.