Uremic encephalopathy (UE) is a relatively new entity, resulting from a variety of
metabolic alterations associated with acute or chronic renal failure. It has a heterogeneous
presentation, most often an acute or subacute onset of neurological symptoms including
headaches, seizures, confusion, asterixis, ataxia or motor dysfunction [
[1]
]. Magnetic Resonance Imaging (MRI) findings and clinical presentation have led to
the description of two variants of UE: a cortical type, closely related to posterior
reversible encephalopathy syndrome (PRES), and a basal ganglia (BG) type, occurring
most often in diabetics [
1
,
2
]. MRI changes consist of reversible vasogenic edema. We present the case of a patient
with UE and isolated involvement of the centrum semiovale, an extremely rare presentation.
Only two other similar cases are reported in the literature [
2
,
3
], with identical imaging findings, suggestive of a new type of UE.To read this article in full you will need to make a payment
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References
- Neurological complications of hemodialysis: state of the art.J Nephrol. 2012; 25: 170-182
- Uremic encephalopathy with atypical magnetic resonance features on diffusion-weighted images.Korean J Radiol. 2012; 13: 808-811
- Reversible cytotoxic brain edema and facial weakness in uremic encephalopathy.J Neurol. 2009; 256: 1372-1373
- Posterior reversible encephalopathy syndrome caused by hypertensive encephalopathy and acute uremia.Neurocrit Care. 2006; 4: 133-136
- Diffusion-weighted magnetic resonance imaging in the syndrome of acute bilateral basal ganglia lesions in diabetic uremia.Mov Disord. 2006; 21: 1267-1270
- Patterns in early diffusion-weighted MRI in children with haemolytic uraemic syndrome and CNS involvement.Eur Radiol. 2012; 22: 506-513
- Takayasu's arteritis and posterior reversible encephalopathy syndrome: a case-based review.Clin Rheumatol. 2013; 32: 409-415
- Posterior reversible encephalopathy syndrome: a case of unusual diffusion-weighted MR images.J Neuroradiol. 2009; 36: 102-105
- Apparent diffusion coefficient restriction in the white matter: going beyond acute brain territorial ischemia.Insights Imaging. 2012; 3: 155-164
- Mechanisms of acute uremic encephalopathy: early activation of Fos and Fra-2 gene products in different nuclei/areas of the rat brain.J Ren Nutr. 2010; 20: S44-S50
Article info
Publication history
Published online: July 16, 2014
Accepted:
July 8,
2014
Received in revised form:
July 4,
2014
Received:
May 15,
2014
Identification
Copyright
© 2014 Elsevier B.V. Published by Elsevier Inc. All rights reserved.