Highlights
- •Many predictors of intracerebral hemorrhage outcomes related to hematoma volume.
- •The cut-off for hematoma volume, to be considered large, ranged between 20 and 30 mL.
- •Hematoma volume and re-bleed, growth, or expansion are directly related.
- •The association of hematoma volume and growth indentifies areas for intervention.
- •Hematoma volume is perhaps the most important variable when determining outcomes.
Abstract
Intracerebral hemorrhage (ICH) is a leading cause of morbidity and mortality, greatly
linked to hematoma volume. Understanding the characteristics and size of hematoma
is integral to evaluating severity and prognosis after ICH. Examination of the literature
suggests that markers for hematoma size vary, but the key range between 20–30 mL is most widely used as the cut-off for classification of hematoma volume. The role
of hematoma volume in episodes of hematoma expansion and re-bleeding further impact
outcomes, with increased growth associated with larger hematoma volume. Additionally,
many commonly used predictors of ICH outcomes are directly related to hematoma volume,
implicating it as an important variable when determining outcomes. In conclusion,
hematoma volume is likely the most significant determinant of outcomes in intracerebral
hemorrhage.
Keywords
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Article info
Publication history
Published online: July 05, 2014
Accepted:
June 30,
2014
Received in revised form:
May 21,
2014
Received:
March 13,
2014
Identification
Copyright
© 2014 Elsevier B.V. Published by Elsevier Inc. All rights reserved.