Abstract
Objective
The aim of this study was to identify factors associated with neuropsychological rehabilitation
outcome in patients with multiple sclerosis (MS).
Methods
Ninety-eight relapsing–remitting MS patients received multimodal neuropsychological
intervention (attention retraining, teaching compensatory strategies, psychoeducation,
psychological support, and homework assignments) conducted once a week in 60-minute
sessions during thirteen consecutive weeks. The evaluated factors included: 1) patient-related
(baseline objective and subjective cognitive performance, mood, fatigue, as well as
demographic factors); 2) illness-related (duration and severity of the disease); and
3) intervention-related factors (amount of computer-based attention exercises and
homework assignments, therapist's evaluation of the benefit, and therapist).
Results
Patient-related factors affected rehabilitation outcome, whereas illness- and intervention-related
factors did not. The results showed that especially MS patients with male gender and
more severe attentional deficits benefitted from the intervention.
Conclusion
Patient-related factors may affect neuropsychological rehabilitation outcome in MS.
Keywords
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Article info
Publication history
Published online: August 22, 2013
Accepted:
July 31,
2013
Received in revised form:
July 26,
2013
Received:
April 18,
2013
Identification
Copyright
© 2013 Elsevier B.V. Published by Elsevier Inc. All rights reserved.
