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MS as a gateway disease

  • Fred D. Lublin
    Correspondence
    Tel.: +1 212 241 6854.
    Affiliations
    The Corinne Goldsmith Dickinson Center for Multiple Sclerosis, Icahn School of Medicine at Mount Sinai, 5 East 98th Street, Box 1138, New York, NY 10029-6574, United States
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Published:April 10, 2013DOI:https://doi.org/10.1016/j.jns.2013.02.014

      Abstract

      Multiple sclerosis (MS) clinical research has produced remarkable results over the past two decades leading to 9 marketed therapies that alter disease course. We have learned a great deal about the science of MS clinical trials, especially for treatments with anti-inflammatory agents. Moving forward, we would now like to apply what we have learned to the new challenges of treating the degenerative aspects of this illness. Doing so will have benefits not only for MS, but potentially for other neurodegenerative diseases.

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