Abstract
Introduction
Chagas disease (CD) is associated with stroke, which can result in significant long-term
disability. Stroke has also been associated with depressive symptoms, which affect
functional performance and quality of life (QOL). Few data are available on the effect
of chagasic stroke on functional performance and QOL.
Objectives
This study aimed to investigate the correlation of stroke disability and depressive
symptoms with functional performance and QOL in chagasic stroke patients.
Methods
In this cross-sectional study, stroke sequelae were assessed using the Modified Rankin
Stroke Scale (MRSS), depressive symptoms using the Beck Depression Inventory (BDI),
functional performance using the Barthel Index (BI), and QOL using the WHOQOL-BREF.
Results
Twenty-one patients with CD and a previous diagnosis of stroke were included. There
was a correlation between the MRSS score and the BI score (r=−0.663, p=0.003), but not the scores of the WHOQOL-BREF subscales. The BDI score was correlated
with the WHOQOL-BREF subscale scores (Physical: r=−0.733, p=0.001; Psychological: r=−0.581, p=0.012; Social: r=−0.713, p=0.001; Environmental: r=−0.659, p=0.003). However, the BDI score was not associated with the BI score (r=0.279, p=0.262).
Conclusions
QOL in patients with CD appears to be influenced more by depressive symptoms than
by the motor-associated consequences of stroke. Conversely, motor sequelae impair
the functionality of the patient more than depressive symptoms.
Keywords
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Article info
Publication history
Published online: October 22, 2012
Accepted:
September 19,
2012
Received in revised form:
September 19,
2012
Received:
January 11,
2012
Identification
Copyright
© 2012 Elsevier B.V. Published by Elsevier Inc. All rights reserved.
