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Vascular dementia

Published:September 25, 2012DOI:https://doi.org/10.1016/j.jns.2012.09.016
      Over the years, more and more data accumulate concerning the role of vascular factors in dementia. The widely-inclusive term 'vascular cognitive impairment' and the more specific 'vascular dementia' cover only a small part of the spectrum. The well-known existence of factors like hypertension, dyslipidemia etc. in what looks like primary degenerative dementia was an unexpected surprise. It is still unclear what the underlying mechanism of the association is, but it fits well with autopsy findings showing mixed brain pathology in the majority of demented individuals' brains. Not unexpectedly, this admixture becomes even more common with advancing age.
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