Over the years, more and more data accumulate concerning the role of vascular factors
in dementia. The widely-inclusive term 'vascular cognitive impairment' and the more
specific 'vascular dementia' cover only a small part of the spectrum. The well-known
existence of factors like hypertension, dyslipidemia etc. in what looks like primary
degenerative dementia was an unexpected surprise. It is still unclear what the underlying
mechanism of the association is, but it fits well with autopsy findings showing mixed
brain pathology in the majority of demented individuals' brains. Not unexpectedly,
this admixture becomes even more common with advancing age.
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Article info
Publication history
Published online: September 25, 2012
Identification
Copyright
© 2012 Published by Elsevier Inc.
