Enteroviral CNS infection is common and its clinical course is usually benign. In immunocompromised patients, however, it can cause meningoencephalitis, presenting with altered mentality and seizure. We describe a previously healthy female patient with enteroviral meningoencephalitis who showed rapidly progressive aphasia. Examination of her cerebrospinal fluid (CSF) showed pleocytosis with lymphocyte dominance, elevated protein, and normal glucose, findings compatible with viral encephalitis. Fluid-attenuated inversion recovery (FLAIR) brain MRI showed hyperintensity in the left frontal and parietal cortices. Enterovirus in the CSF was confirmed by reverse transcriptase-polymerase chain reaction (RT-PCR) of the CSF. Although her neurological deficits had progressed to global aphasia, conservative management resulted in complete improvement within 3 months. This case provides unusual clinical manifestations and imaging findings in enteroviral encephalitis.
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Published online: May 28, 2012
Accepted: May 2, 2012
Received: January 26, 2012
☆This work was supported by a Chung-Ang University research grant.
☆☆Dr. Kim, Dr. Ahn, Dr. Park and Dr. Youn have no financial disclosures.
★Dr. Shin receives institutional research support from Chung-Ang University.
© 2012 Elsevier B.V. Published by Elsevier Inc. All rights reserved.