Abstract
Enteroviral CNS infection is common and its clinical course is usually benign. In
immunocompromised patients, however, it can cause meningoencephalitis, presenting
with altered mentality and seizure. We describe a previously healthy female patient
with enteroviral meningoencephalitis who showed rapidly progressive aphasia. Examination
of her cerebrospinal fluid (CSF) showed pleocytosis with lymphocyte dominance, elevated
protein, and normal glucose, findings compatible with viral encephalitis. Fluid-attenuated
inversion recovery (FLAIR) brain MRI showed hyperintensity in the left frontal and
parietal cortices. Enterovirus in the CSF was confirmed by reverse transcriptase-polymerase
chain reaction (RT-PCR) of the CSF. Although her neurological deficits had progressed
to global aphasia, conservative management resulted in complete improvement within
3 months. This case provides unusual clinical manifestations and imaging findings in
enteroviral encephalitis.
Keywords
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Article info
Publication history
Published online: May 28, 2012
Accepted:
May 2,
2012
Received:
January 26,
2012
Footnotes
☆This work was supported by a Chung-Ang University research grant.
☆☆Dr. Kim, Dr. Ahn, Dr. Park and Dr. Youn have no financial disclosures.
★Dr. Shin receives institutional research support from Chung-Ang University.
Identification
Copyright
© 2012 Elsevier B.V. Published by Elsevier Inc. All rights reserved.
