Research Article| Volume 312, ISSUE 1-2, P36-38, January 15, 2012

Download started.


Midbrain neurocysticercosis presenting as isolated pupil sparing third cranial nerve palsy

Published:September 09, 2011DOI:


      Brainstem alone is involved very infrequently in patients with neurocysticercosis; usually, it occurs in association with disseminated form of the disease. Isolated involvement of the third nerve is commonly due to vascular causes. We are reporting a case due to cysticercus lesion presenting as isolated third-nerve involvement with sparing of the pupil. The diagnosis of neurocysticercosis was established by the presence of characteristic granulomatous lesions in the midbrain along with positive ELISA for cysticercal antigen in the cerebrospinal fluid. The patient responded well to corticosteroids with almost complete recovery. A follow-up MRI scan showed a significant decrease in the size of the lesion.


      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Journal of the Neurological Sciences
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Ranjith M.P.
        • Divya R.
        • Sahni A.
        Isolated third cranial nerve palsy: a rare presentation of neurocysticercosis.
        Ir J Med Sci. 2009;
        • Mokta J.K.
        • Mahajan S.
        • Machhan P.
        • Mokta K.K.
        • Patial R.K.
        • Prashar B.S.
        Recurrent oculomotor nerve palsy: a rare presentation of neurocysticercosis.
        Neurol India. 2004; 52: 402
        • Kim J.S.
        • Jeong S.M.
        • Moon S.Y.
        • Park S.H.
        Third cranial nerve palsy from midbrain neurocysticercosis: repeated exacerbation on tapering corticosteroids.
        J Neuroophthalmol. 2004; 24: 217-220
        • Meena M.K.
        • Khuteta A.
        • Vashishtha R.
        Isolated superior division oculomotor palsy in neurocysticercosis: a rare presentation.
        Br J Ophthalmol. 2010; 94: 954-955
        • Chotmongkol V.
        • Sawanyawisuth K.
        • Limpawattana P.
        • Phuphatham A.
        • Chotmongkol R.
        • Intapan P.M.
        Superior divisional oculomotor nerve palsy caused by midbrain neurocysticercosis.
        Parasitol Int. 2006; 55: 223-225
        • Sawhney I.M.
        • Singh G.
        • Lekhra O.P.
        • et al.
        Uncommon presentations of neurocysticercosis.
        J Neurol Sci. 1998; 54: 94-100
        • Song Tae-Jin
        • Sang Hyun Suh
        • Hanna Cho
        • Kyung-Yul Lee
        Claude's syndrome associated with neurocysticercosis.
        Yonsei Med J. 2010; 51: 978-979
        • Singh N.N.
        • Verma R.
        • Pankaj B.K.
        • Misra S.
        Neurocysticercosis presenting as Weber's syndrome.
        Neurol India. 2003; 53: 551-552
        • Del Bruto O.H.
        • Rajshekhar V.
        • White Jr., A.C.
        • et al.
        Proposed criteria for neurocysticercosis.
        Neurology. 2001; 57: 177-183
        • Castro O.
        • Johnson L.N.
        • Mamourian A.C.
        Isolated interior oblique paresis from brain-stem infarction: perspective on oculomotor fascicular organization in the ventral midbrain tegmentum.
        Arch Neurol. 1990; 47: 235-237
        • Schwartz T.H.
        • Lycette C.A.
        • Kargman D.E.
        Clinicoradiographic evidence for oculomotor fascicular anatomy.
        J Neurol Neurosurg Psychiatry. 1995; 59: 338
        • Breen L.A.
        • Hopf H.C.
        • Farris R.K.
        • Gutman L.
        Pupil-sparing oculomotor nerve palsy due to a midbrain infarction.
        Arch Neurol. 1991; l48: 105-106