Abstract
Background
To evaluate characteristics and mortality related to post-stroke fatigue (PSF).
Methods
All surviving stroke patients admitted to the Stroke Unit, Haukeland University Hospital,
between February 2006 and November 2008 were sent a postal questionnaire including
the Fatigue Severity Scale (FSS), the hospital anxiety and depression scale (HADSD),
and the Barthel Index (BI) at least 6 months after stroke onset. Survival among patients returning the questionnaire was
determined by November 2009. PSF was defined as FSS score≥5.
Results
Among 377 patients returning the questionnaire, 42.3% had PSF. Logistic regression
showed that PSF was independently associated with pre-stroke depression, leucoaraiosis,
myocardial infarction, diabetes mellitus, pain, and sleeping disturbances. Mean FSS
score was lower among TIA patients than among patients with minor cerebral infarction
(patients with BI=100) (P=.002). Cox regression analysis showed mortality to be associated with PSF.
Conclusion
There is a multifactorial basis for PSF suggesting different therapy options. Cerebral
lesions may cause PSF in some patients. Post-stroke fatigue is associated with higher
mortality.
Keywords
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Article info
Publication history
Published online: August 24, 2011
Accepted:
August 2,
2011
Received:
February 17,
2011
Identification
Copyright
© 2011 Elsevier B.V. Published by Elsevier Inc. All rights reserved.
