Abstract
This study investigated slow waves (SW; >75 μV and <4 Hz) characteristics in patients with idiopathic rapid eye movement (REM) sleep behavior
disorder (iRBD). Thirty patients with iRBD and 30 age- and sex-matched healthy subjects
underwent one polysomnographic (PSG) nocturnal sleep recording. SW automatic detection
was performed on F3, C3, P3, and O1 leads and SW characteristics were derived (SW
density, amplitude, frequency, slope, and duration of negative and positive phases).
We also compared iRBD patients and control subjects on PSG variables and delta (0.25–4.0 Hz) spectral power. No between-group differences were found on PSG variables, delta
spectral power, or SW characteristics. Results show no SW abnormalities in iRBD patients
compared to healthy participants, which suggests similar level of synchronization
of thalamo-cortical neurons during N-REM sleep.
Keywords
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Article info
Publication history
Published online: June 30, 2011
Accepted:
June 9,
2011
Received in revised form:
May 24,
2011
Received:
March 15,
2011
Footnotes
☆J.M. received personal compensation as a consultant and/or honoraria and/or travel and accommodation expenses covered or reimbursed by Valeant Pharmaceuticals International, GlaxoSmithKline, Sanofi-aventis, Boehringer Ingelheim, Servier, and Shire; is a board member of Boehringer Ingelheim, Servier, and Merck; is a speaker for Boehringer and Shire; and received financial support for research activities from Sanofi-aventis and GlaxoSmithKline. V.L., J.C., M.L. and J.-F.G. have nothing to report.
Identification
Copyright
© 2011 Elsevier B.V. Published by Elsevier Inc. All rights reserved.
