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Non-rapid eye movement sleep characteristics in idiopathic REM sleep behavior disorder

  • Véronique Latreille
    Affiliations
    Centre for Advanced Research in Sleep Medicine, Hôpital du Sacré-Cœur de Montréal, Quebec, Canada

    Department of Psychology, Université de Montréal, Quebec, Canada
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  • Julie Carrier
    Affiliations
    Centre for Advanced Research in Sleep Medicine, Hôpital du Sacré-Cœur de Montréal, Quebec, Canada

    Department of Psychology, Université de Montréal, Quebec, Canada
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  • Jacques Montplaisir
    Affiliations
    Centre for Advanced Research in Sleep Medicine, Hôpital du Sacré-Cœur de Montréal, Quebec, Canada

    Department of Psychiatry, Université de Montréal, Quebec, Canada
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  • Marjolaine Lafortune
    Affiliations
    Centre for Advanced Research in Sleep Medicine, Hôpital du Sacré-Cœur de Montréal, Quebec, Canada

    Department of Psychology, Université de Montréal, Quebec, Canada
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  • Jean-François Gagnon
    Correspondence
    Corresponding author at: Centre d'Études Avancées en Médecine du Sommeil, Hôpital du Sacré-Cœur de Montréal, 5400 boul. Gouin ouest, Montréal, Québec, H4J 1C5. Tel.: +1 514 338 2693; fax: +1 514 338 2531.
    Affiliations
    Centre for Advanced Research in Sleep Medicine, Hôpital du Sacré-Cœur de Montréal, Quebec, Canada

    Department of Psychology, Université du Québec à Montréal, Quebec, Canada
    Search for articles by this author

      Abstract

      This study investigated slow waves (SW; >75 μV and <4 Hz) characteristics in patients with idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD). Thirty patients with iRBD and 30 age- and sex-matched healthy subjects underwent one polysomnographic (PSG) nocturnal sleep recording. SW automatic detection was performed on F3, C3, P3, and O1 leads and SW characteristics were derived (SW density, amplitude, frequency, slope, and duration of negative and positive phases). We also compared iRBD patients and control subjects on PSG variables and delta (0.25–4.0 Hz) spectral power. No between-group differences were found on PSG variables, delta spectral power, or SW characteristics. Results show no SW abnormalities in iRBD patients compared to healthy participants, which suggests similar level of synchronization of thalamo-cortical neurons during N-REM sleep.

      Keywords

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