Abstract
Parkinson's Disease Dementia (PD-D) is one of the most important non-motor signs in
advanced PD and is the most influencing factor predicting nursing home placement.
PD-related Mild Cognitive Impairment (PD-MCI) is a potential prodromal stage of PD-D.
The Grand Total EEG (GTE) score is a rating scale for clinical EEG (Electroencephalography)
analyses which is useful in the evaluation of different types of dementia. The purpose
of the present study was to investigate the relationship between a short version of
the GTE score and severity of cognitive deficits in PD. Nineteen patients with PD
underwent neuropsychological testing and resting state EEG. Significant correlations
with deteriorating cognition (combined Mini Mental Status Examination/Clock Drawing
Test) were found for the overall short GTE score (Spearman Rank correlation, ρ=−.6; p<.05) and for the subscore “Frequency of Rhythmic Background Activity” (ρ=−.6; p<.05), indicating that these EEG measures increase with deteriorating cognition.
Keywords
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Article info
Publication history
Published online: June 27, 2011
Accepted:
May 27,
2011
Received in revised form:
May 18,
2011
Received:
March 30,
2011
Identification
Copyright
© 2011 Elsevier B.V. Published by Elsevier Inc. All rights reserved.
