Abstract
Several clinical courses have been defined in multiple sclerosis (MS), but uncertainty
remains as to whether they reflect different neuropathological mechanisms. Two recent
concepts have emerged which could influence the treatment strategy adopted in MS:
- −inflammation drives axonal damage;
- −disability progression in MS follows a two-stage process.
Keywords
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Article info
Publication history
Published online: October 21, 2010
Accepted:
September 20,
2010
Received in revised form:
September 14,
2010
Received:
June 17,
2010
Identification
Copyright
© 2010 Elsevier B.V. Published by Elsevier Inc. All rights reserved.