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Research Article| Volume 298, ISSUE 1-2, P61-63, November 15, 2010

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Asian over-representation among patients with hemifacial spasm compared to patients with cranial–cervical dystonia

  • Yuncheng Wu
    Affiliations
    Department of Neurology, Shanghai First People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

    Parkinson's Disease Center and Movement Disorder Clinic, Department of Neurology, Baylor College of Medicine, Houston, TX, USA

    Parkinson's Disease Research Laboratory, Department of Neurology, Baylor College of Medicine, Houston, TX, USA
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  • Anthony L. Davidson
    Affiliations
    Parkinson's Disease Center and Movement Disorder Clinic, Department of Neurology, Baylor College of Medicine, Houston, TX, USA
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  • Tianhong Pan
    Affiliations
    Parkinson's Disease Research Laboratory, Department of Neurology, Baylor College of Medicine, Houston, TX, USA
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  • Joseph Jankovic
    Correspondence
    Corresponding author. Parkinson's Disease Center and Movement Disorder Clinic, Department of Neurology, Baylor College of Medicine, One Baylor Plaza, MS NB302, Houston 77030, TX, USA. Tel.: +1 713 798 7438; fax: +1 713 798 6808.
    Affiliations
    Parkinson's Disease Center and Movement Disorder Clinic, Department of Neurology, Baylor College of Medicine, Houston, TX, USA
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Published:September 28, 2010DOI:https://doi.org/10.1016/j.jns.2010.08.017

      Abstract

      Background and purpose

      Hemifacial spasm (HFS) is a common movement disorder, but its prevalence in different populations has not been elucidated.

      Methods

      We reviewed all patients with HFS currently followed at the Baylor College of Medicine Movement Disorders Clinic and compared their demographic and clinical data with a control group of patients with cranial–cervical dystonia (CD).

      Results

      In contrast to patients with CD (N=145, mean age 48.64±13.61 years), of whom 117 (80.69%) were Caucasians, 13 (8.97%) Hispanic, 10 (6.90%) African-American, and 5 (3.45%) were of Asian origin, there were 81 (61.36%) Caucasians, 24 (18.18%) Hispanic, 13 (9.85%) African-Americans, and 14 (10.61%) Asians in the HFS group (N=132, mean age 49.33±13.25). Although there was no statistical difference in the age and gender distribution between the two groups, the frequency of Asians in HFS group was 3.1 times higher than that in CD group (P<0.01). Furthermore, the prevalence of Asians among patients with HFS was nearly twice the estimated prevalence of Asians in a general Houston population (5.48%).

      Conclusion

      Our results support the observation that HFS is much more common in the Asian population than in other populations. Further epidemiological, genetic, imaging and anatomic studies are needed to understand the apparent difference in the prevalence of this peripherally induced movement disorder.

      Keywords

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