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Review article| Volume 298, ISSUE 1-2, P11-16, November 15, 2010

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The pre-requisite of a second-generation glioma PET biomarker

  • Katalin Borbely
    Correspondence
    Corresponding author. Tel.: +36 1 224 8600; fax: +36 1 224 8720.
    Affiliations
    PET/CT Amb, National Institute of Oncology, 1122 Budapest, Rath Gyorgy 7-9, Hungary
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  • Author Footnotes
    1 Tel.: +1 434 243 9312; fax: +1 434 982 5753.
    Max Wintermark
    Footnotes
    1 Tel.: +1 434 243 9312; fax: +1 434 982 5753.
    Affiliations
    Neuroradiology Division, University of Virginia, Department of Radiology, Charlottesville, VA, USA
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  • Author Footnotes
    2 Tel.: +36 1 2512999; fax: +36 1 2515678.
    Janos Martos
    Footnotes
    2 Tel.: +36 1 2512999; fax: +36 1 2515678.
    Affiliations
    Department of Neuroradiology, National Institute of Neurosurgery, 1145 Budapest, Amerikai 45, Hungary
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  • Author Footnotes
    2 Tel.: +36 1 2512999; fax: +36 1 2515678.
    Imre Fedorcsak
    Footnotes
    2 Tel.: +36 1 2512999; fax: +36 1 2515678.
    Affiliations
    Department of Neurosurgery, National Institute of Neurosurgery, 1145 Budapest, Amerikai 45, Hungary
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  • Author Footnotes
    3 Tel.: +36 52 411 717; fax: +36 52 419 418.
    Laszlo Bognar
    Footnotes
    3 Tel.: +36 52 411 717; fax: +36 52 419 418.
    Affiliations
    Department of Neurosurgery, Debrecen University Medical Faculties, 4032 Debrecen, Nagyerdei krt 98, Hungary
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    4 Tel.: +36 1 224 8600; fax: +36 1 8667.
    Miklos Kasler
    Footnotes
    4 Tel.: +36 1 224 8600; fax: +36 1 8667.
    Affiliations
    National Institute of Oncology, 1122 Budapest, Rath Gyorgy 7-9, Hungary
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  • Author Footnotes
    1 Tel.: +1 434 243 9312; fax: +1 434 982 5753.
    2 Tel.: +36 1 2512999; fax: +36 1 2515678.
    3 Tel.: +36 52 411 717; fax: +36 52 419 418.
    4 Tel.: +36 1 224 8600; fax: +36 1 8667.
Published:August 26, 2010DOI:https://doi.org/10.1016/j.jns.2010.07.024

      Abstract

      Since the introduction of FDG into the field of molecular imaging with positron emission tomography (PET) more than three decades ago, FDG has been the tracer of choice for oncology PET imaging. Despite the relative disadvantages of FDG and the relative benefits of its challengers, FDG remains the most commonly used glioma tracer nowadays. The present article surveys the expectations of the field and gives a concise summary of recent developments; including the issues pertaining to the continued search for an optimal second-generation PET biomarker for glioma.

      Mini-abstract

      The present article gives a concise summary of recent developments; including the issues pertaining to the continued search for an optimal PET biomarker for glioma.

      Keywords

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