Book review| Volume 298, ISSUE 1-2, P170-171, November 15, 2010

Book review

Published:August 27, 2010DOI:
      Understanding disease pathology regarding disorders of the nervous and vascular systems as well as successfully treating both acute and chronic degenerative diseases has proven to be one of the most challenging issues the scientific and medical communities have faced in the past century. It is estimated that more than 500 million individuals worldwide are suffering from such disorders as stroke, Alzheimer's-type dementia, Parkinson's disease, traumatic brain injury, mild cognitive impairment, and hypertension. It is predicted that, in the coming years, this number is likely to increase significantly. One reason for this is the significant risks associated with the nervous and vascular systems. Recent observations have shown that organs, such as the brain, are highly susceptible to cellular injury via free radical oxidation due to the large amount of oxygen consumed by the brain and the relatively limited ability to overcome cellular injury, and it is theorized that these factors lead to the production of cellular oxidative stress. Current studies estimate that the high levels of oxidative stress could potentially play a significant role in the onset of pathological complications as well as being a major player in aging mechanisms.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Journal of the Neurological Sciences
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect