Abstract
Objective
To investigate whether quantitative EEG may be useful in differential diagnosis of
AD and SVD and to determine the correlation between dementia and abnormalities in
EEG.
Materials and methods
The group under study was consisted of 62 patients with AD (mean age: 73.6 yrs; M
51%), 31 with SVD (mean age: 75.2 yrs, M 43%) and a control group of 14 healthy subjects
(mean age: 69.5 yrs, M 43%). The patients were divided into subgroups of those with
mild, moderate and marked dementia. EEG findings were classified using eight-degree
scale according to the presence of slow waves, and then quantitative analysis was
carried out by calculating the alpha/slow wave power ratios and the mean frequencies
in all and some selected derivations.
Results
A significant difference between visual EEGs and QEEGs in AD and SVD was found. Only
QEEG parameters differed in AD and SVD subgroups with the same degree of cognitive
impairment: the mean wave frequencies of waves in temporal derivations in subgroups
with mild and moderate dementia and alpha/delta waves power ratio in subgroups with
moderate dementia.
Conclusions
Visual EEGs and QEEGs could be used in addition to the differential diagnosis between
AD and SVD, but only selected parameters of QEEG could be useful in differentiating
between AD and SVD subgroups with the same degree of dementia.
Keywords
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Article info
Publication history
Published online: March 09, 2009
Footnotes
☆The permission to carry out the research was obtained from the Bioethics Commitee of the Medical University of Warsaw.
Identification
Copyright
© 2009 Elsevier B.V. Published by Elsevier Inc. All rights reserved.
