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Research Article| Volume 283, ISSUE 1-2, P95-98, August 15, 2009

“Real life” executive deficits in patients with focal vascular lesions affecting the cerebellum

  • Author Footnotes
    1 These two authors contributed equally to this work.
    Facundo Manes
    Correspondence
    Corresponding author. Institute of Cognitive Neurology (INECO), Castex 3293 (1425), Buenos Aires, Argentina.
    Footnotes
    1 These two authors contributed equally to this work.
    Affiliations
    Institute of Cognitive Neurology (INECO), Buenos Aires, Argentina

    Raúl Carrea Institute for Neurological Research, Buenos Aires, Argentina

    Institute of Neuroscience, Favaloro University, Buenos Aires, Argentina
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  • Author Footnotes
    1 These two authors contributed equally to this work.
    Agustina Ruiz Villamil
    Footnotes
    1 These two authors contributed equally to this work.
    Affiliations
    Raúl Carrea Institute for Neurological Research, Buenos Aires, Argentina
    Search for articles by this author
  • Sebastián Ameriso
    Affiliations
    Raúl Carrea Institute for Neurological Research, Buenos Aires, Argentina
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  • María Roca
    Affiliations
    Institute of Cognitive Neurology (INECO), Buenos Aires, Argentina

    Raúl Carrea Institute for Neurological Research, Buenos Aires, Argentina

    Institute of Neuroscience, Favaloro University, Buenos Aires, Argentina
    Search for articles by this author
  • Teresa Torralva
    Affiliations
    Institute of Cognitive Neurology (INECO), Buenos Aires, Argentina

    Raúl Carrea Institute for Neurological Research, Buenos Aires, Argentina

    Institute of Neuroscience, Favaloro University, Buenos Aires, Argentina
    Search for articles by this author
  • Author Footnotes
    1 These two authors contributed equally to this work.
Published:March 06, 2009DOI:https://doi.org/10.1016/j.jns.2009.02.316

      Abstract

      The aim of this study was to investigate everyday executive functioning abilities in patients with focal cerebellar lesions using an executive battery sensitive for the detection of damage to the prefrontal cortex, including a “real life” situation task. Eleven patients with focal cerebellar infarcts were studied prospectively after their injury. All subjects underwent a complete neurological, neuropsychiatric, and neuropsychological examination, as well as a specific computerized battery (Test of Attentional Performance), and an “ecological” test: the Multiple Errands Task-hospital version (MET-hv, adapted version). Significant differences were found between patients and normal controls in language and executive functions tasks. Significant differences were observed in the flexibility subscale of the Test of Attentional Performance and several subscales of the MET-hv (total amount of failures, interpretation failures, task completion score, and inefficiencies subscale). This study supports previous reports showing a pattern of cognitive abnormalities following focal cerebellar damage that includes impairments of executive function. Moreover, it suggests that the ecological test used in this investigation might be useful for the detection of deficits in real-life executive functioning among this patient population.

      Keywords

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