Neuroprotective effect is the most significant among the therapeutic actions of vinpocetine.
It is related to the inhibition of the operation of voltage dependent neuronal Na
(+)-channels, indirect inhibition of some molecular cascades initiated by the rise
of intracellular Ca (++)-levels and inhibition of adenosine reuptake. In addition,
vinpocetine improves cerebral perfusion globally by reducing the vascular tone of
cerebral vessels and normalizing the rheologic properties of the blood.
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© 2009 Published by Elsevier Inc.
