Abstract
Information on autonomic modulation can be derived from different organs that are
innervated by the sympathetic and the parasympathetic nervous system, when assessing
e.g. heart rate or blood pressure fluctuations or the pupil's reaction to light. Correlations
between parameters from different target organs might reveal information on hierarchically
higher centres of autonomic integration.
Here, we obtained parameters of heart rate variability, blood pressure variability,
baroreflex function and light reaction pupillography from 50 individuals and tested
the hypothesis that these are associated.
Pupil diameter and constriction latency significantly correlated with parameters of
heart rate variability, but not with those of blood pressure variability. In contrast,
relative amplitude significantly correlated with blood pressure variability only.
In conclusion, the different branches of the autonomic nervous system examined here
are not associated unequivocally but show a distinct pattern of interrelations in
healthy subjects. Examinations as described here might add to the diagnosis of autonomic
dysfunction and reveal differential patterns in certain disease states.
Keywords
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Article info
Publication history
Published online: February 06, 2009
Accepted:
January 13,
2009
Received:
November 19,
2008
Identification
Copyright
© 2008 Elsevier B.V. Published by Elsevier Inc. All rights reserved.
