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Research Article| Volume 276, ISSUE 1-2, P115-117, January 15, 2009

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Reliability of TMS motor evoked potentials in quadriceps of subjects with chronic hemiparesis after stroke

  • Lewis A. Wheaton
    Affiliations
    Baltimore Veterans Affairs Medical Center GRECC, USA
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  • Federico Villagra
    Affiliations
    Department of Physical Therapy and Rehabilitation Science, University of Maryland School of Medicine, USA
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  • Daniel F. Hanley
    Affiliations
    Department of Neurology, University of Maryland School of Medicine, USA

    Division of Brain Injury Outcome, Department of Neurology, Johns Hopkins University, USA
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  • Richard F. Macko
    Affiliations
    Baltimore Veterans Affairs Medical Center GRECC, USA

    Department of Neurology, University of Maryland School of Medicine, USA

    Department of Medicine, Divisions of Gerontology and Rehabilitation Medicine, University of Maryland School of Medicine, USA
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  • Larry W. Forrester
    Correspondence
    Corresponding author. Rehabilitation Research Service, Baltimore VAMC & Department of Physical Therapy & Rehabilitation Science, Department of Neurology, University of Maryland School of Medicine, 100 Penn Street, Suite 115 Baltimore, MD 21201. Tel.: +1 410 706 5212; fax: +1 410 706 6387.
    Affiliations
    Baltimore Veterans Affairs Medical Center GRECC, USA

    Department of Physical Therapy and Rehabilitation Science, University of Maryland School of Medicine, USA

    Department of Neurology, University of Maryland School of Medicine, USA
    Search for articles by this author

      Abstract

      Transcranial magnetic stimulation (TMS) non-invasively measures excitability of central motor pathways in humans and is used to characterize neuroplasticity after stroke. Using TMS to index lower extremity neuroplasticity after gait rehabilitation requires test–retest reliability. This study assesses the reliability of TMS-derived variables measured at bilateral quadriceps of chronic hemiparetic stroke survivors. Results support using measures of both paretic and nonparetic motor threshold, motor evoked potential (MEP) latencies; and nonparetic MEP amplitudes. Implications for longitudinal research are discussed.

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