This paper is only available as a PDF. To read, Please Download here.
Abstract
The records of 1428 neurological patients referred to a department of Clinical Neurophysiology
for PRVER testing have been reviewed. Half field studies with multichannel recordings
were carried out in the majority. 1186 of these patients had a provisional diagnosis
of MS; 42% had abnormal PRVERs compared with 25% for those patients who did not have
MS. Symmetrical latency increases from stimulation of either eye, interocular latency
abnormalities and amplitude abnormalities were as frequent in the non-MS patients
as the group with a provisional diagnosis of MS. A small proportion of patients had
neurophysiological evidence of field defects; homonymous hemianopias occurred as frequently
as “central” defects in the MS group. The PRVER abnormalities are considered in relation
to the current models of conduction in demyelinated fibres.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Journal of the Neurological SciencesAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Pattern-onset visual evoked responses in suspected multiple sclerosis.J. Neurol. Neurosurg. Psychiat. 1981; 44: 608-614
- Visual evoked responses in the diagnosis and management of patients suspected of multiple sclerosis.Brain. 1975; 98: 261-282
- Cortical abnormalities and the visual evoked response.in: Doc. Ophthal. Proc. Series. 27. 1981: 347-365
- The effect of experimental “scotomata” on the ipsilateral and contralateral responses to pattern reversal in one half field.Electroenceph. Clin. Neurophysiol. 1978; 45: 376-392
- The pattern-evoked potential in lesions of the posterior visual pathways.Ann. N.Y. Acad. Sci. 1982; 388: 264-289
- The pattern visual evoked potential in the clinical assesment of undiagnosed spinal cord disease.in: Courjon J Mauguière F Revol M Clinical Applications of Evoked Potentials. Raven Press, New York1982: 463-471
- Recovery and function after demyelination.in: Sears T.A Neuronal-Glial Cell Interrelationships. Springer-Verlag, Berlin1982: 287-302 (Dahlem Konferenzen)
- The internodal axon membrane — Electrical excitability and continuous conduction in segmental demyelination.J. Physiol. (Lond.). 1978; 280: 273-301
- Effects of luminance on the pattern visual evoked potential in multiple sclerosis.Electroenceph. Clin. Neurophysiol. 1978; 45: 496-504
- The incidence and nature of visual pathway involvement in Friedreich's ataxia.Brain. 1980; 103: 413-434
- Pathophysiology of demyelinating disease.Brit. Med. Bull. 1977; 33: 21-27
- Visual evoked responses in the diagnosis of multiple sclerosis.Brit. Med. J. 1973; IV: 661-664
- The pattern-evoked potential in compression of the anterior visual pathway.Brain. 1976; 99: 357-374
- The macular and paramacular subcomponents of the pattern evoked response.in: Lehmann D Callaway E Human Evoked Potentials — Applications and Problems. Plenum Press, New York1979: 135-151
- The comparison of small-size rectangle and checkerboard stimulations for the evaluation of delayed visual evoked responses in patients suspected of multiple sclerosis.Brain. 1977; 100: 119-136
- Abnormalities of the pattern visual evoked potential in patients with homonymous visual field defects.in: Barber C Evoked Potentials. MTP Press, Lancaster1980: 285-291
- Visual evoked potentials from quadrantic field stimulation in the investigation of homonymous field defects.in: Barber C Evoked Potentials. MTP Press, Lancaster1980: 279-283
- Pathophysiology of conduction in central nerve fibres.in: Desmedt J.E Visual Evoked Potentials in Man — New Developments. Clarendon Press, Oxford1977: 121-133
- The pattern reversal evoked visual potential in the diagnosis of multiple sclerosis.J. Neurol. Neurosurg. Psychiat. 1977; 40: 1009-1014
- Visual, auditory, and somatosensory pathway involvement in hereditary cerebellar ataxia, Friedreich's ataxia and familial spastic pareplegia.Electroenceph. Clin. Neurophysiol. 1981; 52: 283-297
- Internodal conduction in undissected demyelinated nerve fibres.J. Physiol. (Lond.). 1972; 227: 323-350
- Delayed visual perception and delayed visual evoked potential in the spinal form of multiple sclerosis and in retrobulbar neuritis.Brain. 1976; 99: 43-63
- Visually evoked potentials in Friedreich's ataxia.in: Courjon J Mauguière F Revol M Clinical Applications of Evoked Potentials in Neurology. Raven Press, New York1982: 131-139
Article info
Publication history
Accepted:
January 12,
1984
Received in revised form:
December 19,
1983
Received:
July 15,
1983
Identification
Copyright
© 1984 Published by Elsevier Inc.
