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The records of 1428 neurological patients referred to a department of Clinical Neurophysiology for PRVER testing have been reviewed. Half field studies with multichannel recordings were carried out in the majority. 1186 of these patients had a provisional diagnosis of MS; 42% had abnormal PRVERs compared with 25% for those patients who did not have MS. Symmetrical latency increases from stimulation of either eye, interocular latency abnormalities and amplitude abnormalities were as frequent in the non-MS patients as the group with a provisional diagnosis of MS. A small proportion of patients had neurophysiological evidence of field defects; homonymous hemianopias occurred as frequently as “central” defects in the MS group. The PRVER abnormalities are considered in relation to the current models of conduction in demyelinated fibres.
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- Pattern-onset visual evoked responses in suspected multiple sclerosis.J. Neurol. Neurosurg. Psychiat. 1981; 44: 608-614
- Visual evoked responses in the diagnosis and management of patients suspected of multiple sclerosis.Brain. 1975; 98: 261-282
- Cortical abnormalities and the visual evoked response.in: Doc. Ophthal. Proc. Series. 27. 1981: 347-365
- The effect of experimental “scotomata” on the ipsilateral and contralateral responses to pattern reversal in one half field.Electroenceph. Clin. Neurophysiol. 1978; 45: 376-392
- The pattern-evoked potential in lesions of the posterior visual pathways.Ann. N.Y. Acad. Sci. 1982; 388: 264-289
- The pattern visual evoked potential in the clinical assesment of undiagnosed spinal cord disease.in: Courjon J Mauguière F Revol M Clinical Applications of Evoked Potentials. Raven Press, New York1982: 463-471
- Recovery and function after demyelination.in: Sears T.A Neuronal-Glial Cell Interrelationships. Springer-Verlag, Berlin1982: 287-302 (Dahlem Konferenzen)
- The internodal axon membrane — Electrical excitability and continuous conduction in segmental demyelination.J. Physiol. (Lond.). 1978; 280: 273-301
- Effects of luminance on the pattern visual evoked potential in multiple sclerosis.Electroenceph. Clin. Neurophysiol. 1978; 45: 496-504
- The incidence and nature of visual pathway involvement in Friedreich's ataxia.Brain. 1980; 103: 413-434
- Pathophysiology of demyelinating disease.Brit. Med. Bull. 1977; 33: 21-27
- Visual evoked responses in the diagnosis of multiple sclerosis.Brit. Med. J. 1973; IV: 661-664
- The pattern-evoked potential in compression of the anterior visual pathway.Brain. 1976; 99: 357-374
- The macular and paramacular subcomponents of the pattern evoked response.in: Lehmann D Callaway E Human Evoked Potentials — Applications and Problems. Plenum Press, New York1979: 135-151
- The comparison of small-size rectangle and checkerboard stimulations for the evaluation of delayed visual evoked responses in patients suspected of multiple sclerosis.Brain. 1977; 100: 119-136
- Abnormalities of the pattern visual evoked potential in patients with homonymous visual field defects.in: Barber C Evoked Potentials. MTP Press, Lancaster1980: 285-291
- Visual evoked potentials from quadrantic field stimulation in the investigation of homonymous field defects.in: Barber C Evoked Potentials. MTP Press, Lancaster1980: 279-283
- Pathophysiology of conduction in central nerve fibres.in: Desmedt J.E Visual Evoked Potentials in Man — New Developments. Clarendon Press, Oxford1977: 121-133
- The pattern reversal evoked visual potential in the diagnosis of multiple sclerosis.J. Neurol. Neurosurg. Psychiat. 1977; 40: 1009-1014
- Visual, auditory, and somatosensory pathway involvement in hereditary cerebellar ataxia, Friedreich's ataxia and familial spastic pareplegia.Electroenceph. Clin. Neurophysiol. 1981; 52: 283-297
- Internodal conduction in undissected demyelinated nerve fibres.J. Physiol. (Lond.). 1972; 227: 323-350
- Delayed visual perception and delayed visual evoked potential in the spinal form of multiple sclerosis and in retrobulbar neuritis.Brain. 1976; 99: 43-63
- Visually evoked potentials in Friedreich's ataxia.in: Courjon J Mauguière F Revol M Clinical Applications of Evoked Potentials in Neurology. Raven Press, New York1982: 131-139
Accepted: January 12, 1984
Received in revised form: December 19, 1983
Received: July 15, 1983
© 1984 Published by Elsevier Inc.